Salmonella Fighting Cancer
THE NEXT BIG THING IN CANCER TREATMENT COULD COME FROM DEADLY BACTERIA., NEXT IN MEDICAL BREAKTHROUGHS. (:25)
ANCHOR LEAD
SOURCE:CDC/about-salmonella.com IT HOSPITALIZES 20-THOUSAND AND KILLS ALMOST FOUR HUNDRED PEOPLE EVERY YEAR. NOW DOCTORS ARE TURNING TO THIS KILLER TO FIGHT CANCER. LOU BAXTER HAS THE STORY.
VO/NARRATION.............
FRED OAKDEN HAS BATTLED COLON CANCER FOR SEVEN YEARS. HE KNOWS IT WILL KILL HIM. (:05)
CG
Fred Oakden
Has Colon Cancer
In: :05
Out: :09 "It's not what you want, but you don't have a whole hell of a lot of choice." (:04)
VO/NARRATION.............
FRED JOINED A UNIQUE STUDY. DOCTOR EDWARD GREENO IS TESTING SALMONELLA TO FIGHT CANCER. (:05)
CG
Edward Greeno, MD
Oncologist
University of Minnesota
Minneapolis, MN
In: :14
Out: :17 "We're trying to induce an immune response with the salmonella." (:03)
VO/NARRATION.............
DOCTORS TRIED THIS 150 YEARS AGO, BUT IT OFTEN KILLED PATIENTS. TODAY, RESEARCHERS CAN ALTER SALMONELLA TO MAKE IT SAFE. (:08)
Edward Greeno, MD
In: :25
Out: :32 "I'm certainly quite hopeful that this going to turn into something that will come into regular clinical use as a valuable agent." (:08)
VO/NARRATION.............
GRAPHIC
In: :32
out: :37 SALMONELLA NATURALLY TRAVELS TO THE G-I TRACT SO COLON AND LIVER CANCERS ARE GOOD TARGETS. (:05)
Edward Greeno, MD
In: :37
Out: :45 "The bacteria, interestingly, actually doesn't just grow inside your body. It actually gets inside the individual cells so that it's right there inside of the tumor cells." (:08)
VO/NARRATION.............
GRAPHIC
In: :45
Out: :57 SALMONELLA ISN'T THE ONLY BACTERIA UNDER STUDY. RESEARCHERS ELSEWHERE ARE TESTING LISTERIA TO FIGHT LIVER CANCER. SCIENTISTS AT THE UNIVERSITY OF FLORIDA ARE STUDYING BACTERIA IN CORAL REEF TO FIGHT CANCER AND BONE DISEASE. (:12)
Edward Greeno, MD
In: :57
Out: 1:03 "We really have the tools now to start manipulating bacteria and make them do the things that we want them to do." (:06)
VO/NARRATION.............
FRED WAS IN THE FIRST PHASE OF THE SALMONELLA STUDY. DOCTOR GREENO SAYS THE DOSE WAS LIKELY TOO SMALL TO IMPACT HIS CANCER. BUT ON HIS LAST SCAN, HALF OF HIS TUMORS SHOWED NO GROWTH. (:10)
Fred Oakden
In: 1:13
Out: 1:14 "I feel really pretty good." (:01)
VO/NARRATION.............
TODAY, FRED SPENDS HIS TIME SHOOTING AND EDITING FOOTAGE OF HIS FAMILY. HE WANTS TO FOCUS NOT ON HIS CANCER, BUT WHAT HE'LL LEAVE BEHIND.
ANCHOR TAG DOCTOR GREENO'S SALMONELLA TRIAL IS NOW IN A PHASE WHERE PATIENTS ARE GETTING HIGHER AND MORE POTENT DOSES OF THE BACTERIA. THE TREATMENT IS EASY - PATIENTS SIMPLY DRINK A SOLUTION THAT CONTAINS SALMONELLA - AND THERE ARE MINIMAL SIDE EFFECTS.
PRODUCER NOTE Please check with your webmaster to make sure he or she has posted the full-length doctor's interview on your Web site to drive viewers to your site.
OPTIONAL ANCHOR TAG...............
CG
http://www.ivanhoe.com IF YOU WOULD LIKE A TRANSCRIPT AND AN ADDRESS TO WRITE TO FOR MORE INFORMATION, CHECK OUT MEDICAL BREAKTHROUGHS ON THE WEB AT IVANHOE-DOT-COM OR SEND A SELF-ADDRESSED, STAMPED ENVELOPE TO:
PRODUCER Please forward a copy of the Research Summary to all inquiries received for more information on this report.
Ivanhoe Broadcast News
2745 W. Fairbanks Ave.
Winter Park, FL 32789
http://www.ivanhoe.com Andrew McIntosh
Executive Producer, Medical News
amcintosh@ivanhoe.com
Direct Line: (407) 691-1516
Viewer Line: (407) 691-1500
MEDICAL BREAKTHROUGHS
RESEARCH SUMMARY
TOPIC: SAVING LIVES WITH SALMONELLA
REPORT: MB #3381
BACKGROUND: Salmonellosis is a type of food poisoning caused by salmonella. Approximately 40,000 cases of salmonellosis are reported each year in the U.S. The University of Minnesota is now conducting a new study and is recruiting male and females, ages 18 and older, to test if salmonella can be used for the treatment cancers surrounding the gut. Their goal is to "weaponize" the salmonella, which allows the bacteria to attack cancer cells in its natural environment.
(SOURCE : www.webmd.com ; www.ahc.umn.edu )
CAUSES OF SALMONELLOSIS: Causes of salmonellosis can vary. Food may be contaminated during the handling process or during food process. It can be causes by food handlers not washing their hands after using the restroom, there for caring the bacteria on their hands. Another cause is by petting certain animals, especially rodents and reptiles. It is advised to wash one's hands after petting these animals in order to prevent the accidental consumption of salmonella.
(SOURCE: www.webmd.com)
SYMPTOMS: The main symptoms that occur with salmonellosis are diarrhea, fever and abdominal cramping.
APPLICATION: Salmonella thrives by finding and staying in the gut and its surrounding areas, such as the liver, spleen and colon. Therefore, scientists want to test the ability to deliver Interlueken 2, or IL-2, with a genetically modified batch of salmonella in order to attack and treat cancerous tumors. Interlueken 2 would trigger an immune attack on the tumors. Tests have been conducted on animals to test the effectiveness of using salmonella as a way to deliver treatment to the cancerous areas. Results have been successful. Researchers suggest that the therapy has potential to be cheaper and less toxic than chemotherapy and radiation.
The study is funded by the National Institutes of Health, The Masonic Cancer Center and Botanic Oil Innovations.
(SOURCE : www.cancer.umn.edu )
FOR MORE INFORMATION, PLEASE CONTACT:
Edward Greeno, MD
University of Minnesota
green048@umn.edu
If this story or any other Ivanhoe story has impacted your life or prompted you or someone you know to seek or change treatments, please let us know by contacting Marsha Hitchcock at mhitchcock@ivanhoe.com.
ANCHOR LEAD
SOURCE:CDC/about-salmonella.com IT HOSPITALIZES 20-THOUSAND AND KILLS ALMOST FOUR HUNDRED PEOPLE EVERY YEAR. NOW DOCTORS ARE TURNING TO THIS KILLER TO FIGHT CANCER. LOU BAXTER HAS THE STORY.
VO/NARRATION.............
FRED OAKDEN HAS BATTLED COLON CANCER FOR SEVEN YEARS. HE KNOWS IT WILL KILL HIM. (:05)
CG
Fred Oakden
Has Colon Cancer
In: :05
Out: :09 "It's not what you want, but you don't have a whole hell of a lot of choice." (:04)
VO/NARRATION.............
FRED JOINED A UNIQUE STUDY. DOCTOR EDWARD GREENO IS TESTING SALMONELLA TO FIGHT CANCER. (:05)
CG
Edward Greeno, MD
Oncologist
University of Minnesota
Minneapolis, MN
In: :14
Out: :17 "We're trying to induce an immune response with the salmonella." (:03)
VO/NARRATION.............
DOCTORS TRIED THIS 150 YEARS AGO, BUT IT OFTEN KILLED PATIENTS. TODAY, RESEARCHERS CAN ALTER SALMONELLA TO MAKE IT SAFE. (:08)
Edward Greeno, MD
In: :25
Out: :32 "I'm certainly quite hopeful that this going to turn into something that will come into regular clinical use as a valuable agent." (:08)
VO/NARRATION.............
GRAPHIC
In: :32
out: :37 SALMONELLA NATURALLY TRAVELS TO THE G-I TRACT SO COLON AND LIVER CANCERS ARE GOOD TARGETS. (:05)
Edward Greeno, MD
In: :37
Out: :45 "The bacteria, interestingly, actually doesn't just grow inside your body. It actually gets inside the individual cells so that it's right there inside of the tumor cells." (:08)
VO/NARRATION.............
GRAPHIC
In: :45
Out: :57 SALMONELLA ISN'T THE ONLY BACTERIA UNDER STUDY. RESEARCHERS ELSEWHERE ARE TESTING LISTERIA TO FIGHT LIVER CANCER. SCIENTISTS AT THE UNIVERSITY OF FLORIDA ARE STUDYING BACTERIA IN CORAL REEF TO FIGHT CANCER AND BONE DISEASE. (:12)
Edward Greeno, MD
In: :57
Out: 1:03 "We really have the tools now to start manipulating bacteria and make them do the things that we want them to do." (:06)
VO/NARRATION.............
FRED WAS IN THE FIRST PHASE OF THE SALMONELLA STUDY. DOCTOR GREENO SAYS THE DOSE WAS LIKELY TOO SMALL TO IMPACT HIS CANCER. BUT ON HIS LAST SCAN, HALF OF HIS TUMORS SHOWED NO GROWTH. (:10)
Fred Oakden
In: 1:13
Out: 1:14 "I feel really pretty good." (:01)
VO/NARRATION.............
TODAY, FRED SPENDS HIS TIME SHOOTING AND EDITING FOOTAGE OF HIS FAMILY. HE WANTS TO FOCUS NOT ON HIS CANCER, BUT WHAT HE'LL LEAVE BEHIND.
ANCHOR TAG DOCTOR GREENO'S SALMONELLA TRIAL IS NOW IN A PHASE WHERE PATIENTS ARE GETTING HIGHER AND MORE POTENT DOSES OF THE BACTERIA. THE TREATMENT IS EASY - PATIENTS SIMPLY DRINK A SOLUTION THAT CONTAINS SALMONELLA - AND THERE ARE MINIMAL SIDE EFFECTS.
PRODUCER NOTE Please check with your webmaster to make sure he or she has posted the full-length doctor's interview on your Web site to drive viewers to your site.
OPTIONAL ANCHOR TAG...............
CG
http://www.ivanhoe.com IF YOU WOULD LIKE A TRANSCRIPT AND AN ADDRESS TO WRITE TO FOR MORE INFORMATION, CHECK OUT MEDICAL BREAKTHROUGHS ON THE WEB AT IVANHOE-DOT-COM OR SEND A SELF-ADDRESSED, STAMPED ENVELOPE TO:
PRODUCER Please forward a copy of the Research Summary to all inquiries received for more information on this report.
Ivanhoe Broadcast News
2745 W. Fairbanks Ave.
Winter Park, FL 32789
http://www.ivanhoe.com Andrew McIntosh
Executive Producer, Medical News
amcintosh@ivanhoe.com
Direct Line: (407) 691-1516
Viewer Line: (407) 691-1500
MEDICAL BREAKTHROUGHS
RESEARCH SUMMARY
TOPIC: SAVING LIVES WITH SALMONELLA
REPORT: MB #3381
BACKGROUND: Salmonellosis is a type of food poisoning caused by salmonella. Approximately 40,000 cases of salmonellosis are reported each year in the U.S. The University of Minnesota is now conducting a new study and is recruiting male and females, ages 18 and older, to test if salmonella can be used for the treatment cancers surrounding the gut. Their goal is to "weaponize" the salmonella, which allows the bacteria to attack cancer cells in its natural environment.
(SOURCE : www.webmd.com ; www.ahc.umn.edu )
CAUSES OF SALMONELLOSIS: Causes of salmonellosis can vary. Food may be contaminated during the handling process or during food process. It can be causes by food handlers not washing their hands after using the restroom, there for caring the bacteria on their hands. Another cause is by petting certain animals, especially rodents and reptiles. It is advised to wash one's hands after petting these animals in order to prevent the accidental consumption of salmonella.
(SOURCE: www.webmd.com)
SYMPTOMS: The main symptoms that occur with salmonellosis are diarrhea, fever and abdominal cramping.
APPLICATION: Salmonella thrives by finding and staying in the gut and its surrounding areas, such as the liver, spleen and colon. Therefore, scientists want to test the ability to deliver Interlueken 2, or IL-2, with a genetically modified batch of salmonella in order to attack and treat cancerous tumors. Interlueken 2 would trigger an immune attack on the tumors. Tests have been conducted on animals to test the effectiveness of using salmonella as a way to deliver treatment to the cancerous areas. Results have been successful. Researchers suggest that the therapy has potential to be cheaper and less toxic than chemotherapy and radiation.
The study is funded by the National Institutes of Health, The Masonic Cancer Center and Botanic Oil Innovations.
(SOURCE : www.cancer.umn.edu )
FOR MORE INFORMATION, PLEASE CONTACT:
Edward Greeno, MD
University of Minnesota
green048@umn.edu
If this story or any other Ivanhoe story has impacted your life or prompted you or someone you know to seek or change treatments, please let us know by contacting Marsha Hitchcock at mhitchcock@ivanhoe.com.
